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LIST OF PUBLICATION
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(I) THESIS :-
Lee AYS. Endogenous opioid peptides and cardiac arrhythmias.
Ph.D. thesis. University of Hong Kong, 1988.
(II) REVIEW ARTICLES:-
1. Lee AYS. Endogenous opioid peptides and cardiac arrhythmias.
Intl J Cardiol 1990; 27:145-51.
2. Lee AYS. Naloxone as an antiarrhythmic agent. Acta Cardiol Sin
1989; 5:301-6.
(III) ORIGINAL ARTICLES:-
1. Lee AYS, Zhan CY, Wong TM. Effects of B-endorphin on the contraction
and electrical activity of the isolated perfused rat heart. Int J Pept Prot Res
1984; 24:525-8.
2. Zhan CY, Lee AYS, Wong TM. Naloxone blocks the cardiac effects of
ischemia and reperfusion in the isolated rat heart. Clin Expt Pharmacol Physiol 1985; 12:373-8.
3. Wong TM, Lee AYS. Cardiac antiarrhythmic evaluation of naloxone with
or without propranolol using a modified chloroform-hypoxia screening test in
the rat. Clin Expt Pharmacol Physiol 1985; 12:379-86.
4. Lee AYS, Wong TM. Naloxone reduces the release of creatine kinase in
the isolated ischemic rat heart. Proc Soc Expt Biol Med 1985; 179(2):219-21.
5. Lee AYS, Zhan CY, Mok CP, Wong TM. A cardiac antiarrhythmic
screening test using the isolated ischemic perfused rat heart preparation. Arch
Int Pharmacol Pharmacodyn 1985; 277(2):217-22.
6. Lee AYS, Unang TWK, Wong TM. Prevention and reversal of ouabain
induced cardiotoxicity of naloxone in the guinea pig. Clin Expt Pharmacol
Physiol 1986; 13:55-8.
7. Huang XD, Lee AYS, Wong TM, Zhan CY, Zhao YY. Naloxone blocks
cardiac arrhythmias due to myocardial ischemia and reperfusion in the
anesthetized dog. Br J Pharmacol 1986; 87:475-7.
8. Lee AYS, Wong TM. Naloxone attenuates augmentation of cAMP levels
and arrhythmias following myocardial ischemia and reperfusion in the isolated perfused rat heart.
Clin Expt Pharmacol Physiol 1986; 13:707-10.
9. Lee AYS,Wong TM. Antiarrhythmic and beneficial effects of naloxone
against cardiotoxicity in the guinea pig following acute ingestion of a lethal dose of ouabain.
Chinese J Physiol Sci 1986; 2(2):154-7.
10. Lee AYS, Wong TM. Antiarrhythmic potency of naloxone determined by a
screening test using the isolated ischemic perfused rat heart preparation. Arch Int Pharmacol Pharmacodyn
1987; 286(2): 212-5.
11. Wong TM, Lee AYS. Chronic morphine treatment reduces the incidence of
ventricular arrhythmias in the isolated rat heart induced by dynorphin(1-13) or myocardial ischemia
and reperfusion. Neurosci Lett 1987; 77:61-5.
12. Lee AYS, Wong TM. Effects of dynorphin 1-13 on cardiac rhythm and cyclic
adenosine monophosphate (cAMP) levels in the isolated perfused rat heart.
Neurosci Lett 1987; 80:289-92.
13. Liu XL, Mok CP, Lee AYS, Wong TM. Evaluation of antiarrhythmic potency of naltrexone
in isolated ischemic rat heart. Acta Pharmacol Sinica 1988; 9(1):40-3.
14. Wong TM, Lee AYS, Chen RKW. Cardiovascular effects of central adminiatration of B-endorphin
in rats receiving neonatal injection of monosodium glutamate. Clin Expt Pharmacol Physiol 1989; 16:19-24.
15. Zhan CY, Tang F, Lee AYS, Wong TM. Effects of reserpine treatment on arrhythmogenesis
during ischemia and reperfusion in the isolated perfused rat heart. Clin Expt Pharmacol Physiol 1989; 16:591-6.
16. Wong TM, Lee AYS, Tai KK. Effects of drugs interacting with opioid receptors during normal
perfusion or ischemia and reperfusion in the isolated rat heart --- An attempt to identify cardiac opioid
receptor subtype(s) involved in arrhythmogenesis. J Mol Cell Cardiol 1990; 22:1167-75.
17. Chen YT, Chang KC, Chen JS, Lin WW, Hu WH, Chang MK,Lee AYS. Aortic and pulmonary input
impedance in patients with cor pulmonale. Japan Heart J 1990; 31(5):619-29.
18. Chen YT, Lee AYS, Chen JS et al. Effects of aging on ventricular function of normal Chinese.
Acta Cardiol Sinica 1990; 6:147-53.
19. Kan MN, Chen YT, Lee AYS. Comparison of transesophageal to transthoracic color doppler
echocardiographic identification of intracardiac mycotic aneurysms in infective endocarditis.
Echocardiography 1991; 6:643-6.
20. Lee AYS, Chen YT, Kan MN, Peng FK, Chai CY, Kuo JS. Consequences of an opiate agonist
and antagonist in myocardial ischemia suggest role of endogenous opioid peptides in ischemic heart
disease. Cardiovasc Res 1992; 26:392-5.
21. Lin CJ, Chen YT, Kuo JS, Lee AYS. Antiarrhythmic action of naloxone: suppression of
picrotoxin-induced cardiac arrhythmias in the rat. Japan Heart J 1992; 33:365-72.
22. Chen YT, Lee AYS, Kan MN et al. Transesophageal echocardiography in adults with a continuous
precordial murmur. Int J Cardiol 1992; 36:61-8.
23. Kan MN, Chen YT, Lee AYS. Naloxone reversal of ischemic arrhythmias is stereospecific and
suggests role of endogenous opioid peptides in ischemic heart disease. Proc Soc Expt Biol Med 1992; 200:518-21.
24. Lee AYS. Stereospecific antiarrhythmic effects of naloxone against myocardial ischemia and
reperfusion in the dog. Br J Pharmacol 1992; 107:1057-60.
25. Lee AYS, Chen YT, Lin CJ, Wu JP, Chen KS. Beneficial effects of the opiate antagonist naloxone
on hemodynamics and ventricular function following coronary artery occlusion and reperfusion in the
dog. Proc Natl Sci Coun ROC 1993; 17:29-34.
26. Wu JP, Chen YT, Lee AYS. Opioids in myocardial ischemia: Effects of dynorphin on ischemic
arrhythmias, bradycardia and cardiogenic shock following coronary artery occlusion in the rat.
Eur Heart J 1993; 14:1273-7.
27. Chen YT, Kan MN, Lee AYS, Chen JS, Chiang BN. Pulmonary venous flow: its relationship to left
atrial and mitral valve motion. J Am Soc Echocardiography 1993; 6(4):387-94.
28. Chen YT, Lin CJ, Lee AYS. Plasma levels of endogenous opioid peptides in patients with acute
myocardial infarction. Japan Heart J 1995; 36(4):421-7.
29. Chen YT, Lin CJ, Lee AYS. Stereospecific effects of naloxone on hemodynamic and
ventricular function following coronary artery occlusion and reperfusion in the dog.
Int J Cardiol 1995; 50:125-9.
30. Leu HS, Lee AYS, Kuo TT. Recurrence of Fusarium solani abscess formation in an
otherwise healthy patient. Infection 1995; 23(5):303-5.
31. Chen YT, Lin CJ, Lee AYS. Ventricular contractile interaction following coronary ligation in dogs.
Chinese Med J 1996; 57(6):385-91.
32. Lee AYS. The blocking effects of nalmefene – a new, potent, and long-lasting opiate antagonist –
against myocardial ischemia-induced arrhythmias in rats. Acta Cardiol Sinica 1998;14:177-82.
33. Chu KM, Lee AYS. Prosthetic valve endocarditis complicating acute obstruction of a
mechanical mitral valve successfully treated with antibiotics and thrombolytic therapy.
Acta Cardiol Sinica 1999; 15(2):99-104.
34. Chang MCK, Lee, AYS, Chen TJ, Chang WF. Acute myocardial infarction after
upper gastrointestinal gastroscopy. Chinese Med J 2001; 64:581-5.
35. Chang MCK, Lee AYS, Chen TJ, Chang WF. Coronary artery spasm induced intimal dissection
in a patient after percutaneous transluminal coronary angioplasty. Acta Cardiol Sinica 2001; 17(3):179-82.
36. Lee AYS, Chang MCK, Chen TJ, Chang WF. Coronary spastic myocardial injury presenting in the
emergency room: A case report. J Emerg Crit Care Med 2001; 12(4):170-4.
37. Lee AYS, Chang MCK, Chen TJ, Chang WF. Left atrial and ventricular ball thrombi complicating
rheumatic heart disease with combined mitral and aortic stenosis. Echocardiography 2001; 18(2):159-161.
38. Lee AYS. Acute myocardial infarction and pulmonary embolism concomitantly associated with
Systemic Lupus Erythematosus. Taiwan Crit Care Med 2002; 4:36-41.
39. Shyu MY, Lee AYS, Lee BJ et al. Right atrial and ventricular thrombi after blunt chest trauma.
J Trauma 2002; 52(4):765-6.
40. Chang MCK, Lee AYS, Chang WF, Chen TJ. Embolic cerebral infarction and
gastrointestinal hemorrhage following thrombolytic therapy for acute myocardial infarction.
Echocardiography 2002; 19(2):139-141.
41. Chang MCK, Lee AYS, Chen TJ, Shyu MY, Chang WF. Percutaneous transluminal adrenal
ablation for aldosteronism: Report of initial 3 cases. Acta Cardiologica Sinica 2002; 18(4):184-7.
42. Lee AYS, Chang MCK, Chen TJ, Shyu MY, Chang WF. Acute coronary syndrome and
hyperthyroidism: Report of 2 cases. Acta Cardiol Sinica, 2003; 19(3):201-4.
43. Lee AYS, Chang MCK, Chen TJ, Chang WF, Shyu MY. Subarachnoid hemorrhage associated with
acute myocardial infarction and sudden death. Taiwan Crit Care Med 2004;6:34-8.
44. Chang MCK, Lee AYS, Lin WY, Chen TJ, Shyu MY, Chang WF. Myocardial and
peripheral concentrations of beta-endorphin before and following myocardial ischemia and
reperfusion during coronary angioplasty. Japanese Heart J 2004;45(3):365-71.
45. Lee AYS, Chang MCK, Chen TJ. Successful use of a guide wire to engage the culprit vessel
following failure of conventional techniques in acute myocardial infarction. Expt Clin Cardiol